Viruses invade the cells of the body –
causing damage and disease in the process. Viruses are intracellular parasites
which cannot reproduce without using the host cell. They lack all the
components to reproduce themselves and so they much “borrow” the host
cell machinery in order to reproduce. This is different than intracellular
bacteria which have all the necessary machinery to reproduce, even though they
must do so while inside the host cell.
For this conference I want you to address
the following: (Remember to update your subject line as always)
Based on what you have learned about
bacteria, viruses and components of living cells, do you consider viruses
alive? Fully explain and support your answer with a discussion
Provide an example of a virus which causes
disease. (Do not duplicate examples).
Describe the disease caused including where
the virus resides/colonizes in the body (ie: in what cell type)?
How does its preferred
“residence” in the body influence the course and spread of the
disease? (ie: How does this virus affect the body specifically. Hint: Do not
provide a list of symptoms here.)
Case Study Scenario
A mother brings her 5 year old daughter
Katie into the emergency room with fever and severe diarrhea. The doctors begin
taking Katie’s history from her mother. Katie is in kindergarten and has a 2
year old sister in day care. Katie’s kindergarten class went on a field trip 3
days ago to a petting zoo. The children were allowed to pet and feed the animals
and were told to wash their hands before having a picnic lunch. Katie was very
excited to eat her favorite lunch of a peanut butter and jelly sandwich that
day. To the mother’s knowledge, none of the other kids in Katie’s class are
ill. The doctor sent samples of Katie’s bloody stool to the lab for analysis.
Lab results showed some blood in her stool
and an unusually high number of gram-negative rods in the sample.
Based on the information presented in the
case study, answer the following questions in your paper (see guidelines for
1. What microorganism do you believe is to
blame for this illness (be specific)? Provide background information on this
organism, history, morphology, virulence factors, toxins, etc…
2. What information from the patient’s
symptoms contributed to your decision? Did this information allow you to rule
out any other possible culprits? What information from the patient’s history
and/or lab samples that contributed to your decision? Support your answers with
factual evidence and logical reasoning.
3. What is the epidemiology of this
disease? Identify risk factors for this disease and describe the disease
course/outcome in humans.
4. What steps can be taken to treat the
illness? How and why are the treatments effective (or ineffective)? Are there
any concerns or other complications of this disease?
Recognize the use of the scientific method
to weigh evidence, make decisions, and solve problems
Apply knowledge of cellular and molecular
processes to understand infectious disease mechanisms
Synthesize knowledge of microbial
pathogenesis and disease prevention methods and communicate this knowledge to
A scientific case study is a short summary
of an event or personal experience that ends in a “mystery”—in this
case, one that you will solve using your own research and the clues provided
within the case study. For this project, you will evaluate a patient-centered
case study that explores a mysterious bacterial or viral illness. The case
study will include a set of questions to guide your analysis.
Your paper should include the following:
Study General Format:
Each of the 4 provided questions should be
answered individually (200-300 words per question answer). You should
incorporate your ideas into well written paragraphs using complete sentences, a
logical flow of information and in-text citations.
Reference citations should be provided at
the end of the document formatted in the APA style.
Your Case study project should include the
Include your name, date and the case study
title (“A”, “B”, “C”, etc…) at the top of your
Number the question answers 1-4 in your
document. DO NOT provide the original questions.
DO NOT copy the original case study into
Answer each of the 4 question sections in
Use in text citations for fact-based
Provide APA formatted full reference
citations at the end of the document.
Remember to use italics as needed for
bacterial genus/species designations.
You must have a minimum of two outside
sources to support your evaluation.
These can consist of any of the following:
books, textbooks, scholarly journal articles, and websites run by reputable
government organizations (such as the CDC or NIH).
You may have additional references as well.
All of your references should be no more than six years old (published in 2005
You should include BOTH in-text citations
and a final reference page formatted in APA style. Please see
httpss://www.umuc.edu/library/citationguides.shtml for additional information on
how to format citations and references in APA style.
All work must be original work written by
you and your group members. Your paper may be checked for plagiarism, so please
make a concerted effort to use and cite your sources appropriately. Any
submitted work that is not your own, or incidences of plagiarism, will be reported
to UMUC administration.